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Beauty & Personal Care Personal Cleaning

Best Yeast Infection Treatments

Updated March 2023
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Pros
Cons
Best of the Best
Monistat One-Day Yeast Infection Treatment
Monistat
One-Day Yeast Infection Treatment
Quick Results

The most powerful yeast infection dosage you can buy over the counter by one of the most trusted brands on the market. Results are fast and effective for most users.

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Quick Results
Bottom Line

The most powerful yeast infection dosage you can buy over the counter by one of the most trusted brands on the market. Results are fast and effective for most users.

Pros

Maximum strength of miconazole nitrate (1,200 milligrams) that requires just one application. Powerful and convenient. Ovule insert is easy to use. Relieves symptoms fast. Includes an applicator and external itch-relief cream.

Cons

The strong, one-day treatment comes with a higher likelihood of side effects than lower milligram treatments, including burning, pain, and itching.

Best Bang for the Buck
Amazon Basic Care Miconazole 1 One-Day Treatment
Amazon Basic Care
Miconazole 1 One-Day Treatment
Good Value

An effective, one-dose treatment by a lesser known brand that will save you a few dollars. Worth the possible side effects for customers who want fast, affordable relief.

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Good Value
Bottom Line

An effective, one-dose treatment by a lesser known brand that will save you a few dollars. Worth the possible side effects for customers who want fast, affordable relief.

Pros

Offers 1,200 milligrams of miconazole nitrate, which is the strongest dose and suitable for quick relief. Insert form is easier to use and less messy than creams. Comes with external itch cream and applicator. Costs less than top brand treatments.

Cons

Pain, itching, and burning sensation are likely due to the high level of medicine in the single dose.

Vagistil Single Dose Yeast Infection Treatment, 3 Pack
Vagistil
Single Dose Yeast Infection Treatment, 3 Pack
Easy to Use

While this one-dose treatment isn't as likely as some competitors to cause side effects, it may not work as well either.

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Easy to Use
Bottom Line

While this one-dose treatment isn't as likely as some competitors to cause side effects, it may not work as well either.

Pros

Contains 6.5% tioconazole, another antifungal that's effective at treating yeast infections. Comes in a pre-dosed applicator that's ready to use. Only one dose required for relief. Comes with soothing anti-itch wipes that are infused with vitamin E and aloe.

Cons

Not all users experienced relief after treatment. Some reports of damaged packaging or close sell by dates.

Monistat Three-Day Yeast Infection Treatment
Monistat
Three-Day Yeast Infection Treatment
Mid-Level Option

Choose this three-day treatment if you prefer a milder dose each time or tend to experience side effects after using one-day treatment options.

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Mid-Level Option
Bottom Line

Choose this three-day treatment if you prefer a milder dose each time or tend to experience side effects after using one-day treatment options.

Pros

Delivers 200 milligrams of nconazole nitrate per dose in a three-day treatment, making it a good option for mild to moderate infections. Easy-to-use ovule insert form. Includes three applicators and cream that soothes external itching.

Cons

Side effects including pain and burning are possible but less likely to occur than when maximum one-day treatments are used.

Monistat Seven-Day Yeast Infection Treatment
Monistat
Seven-Day Yeast Infection Treatment
Best for Mild Infections

Although not as convenient as one- or three-day treatments, this classic seven-day option is worth considering for users who like to distribute the medication over several days.

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Best for Mild Infections
Bottom Line

Although not as convenient as one- or three-day treatments, this classic seven-day option is worth considering for users who like to distribute the medication over several days.

Pros

Low dose formula contains 100 milligrams of miconazole nitrate per application. Not as likely to cause bothersome side effects as higher dose treatments. Also calms external itching and comes with seven applicators.

Cons

Cream form can be messy, and must be used for the full seven days of treatment to achieve the best results. Occasional reports of side effects.

Why trust BestReviews?
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 
HOW WE TESTED

We recommend these products based on an intensive research process that's designed to cut through the noise and find the top products in this space. Guided by experts, we spend hours looking into the factors that matter, to bring you these selections.

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First Reviewed
December 25, 2021
57
Models
considered
18
Hours
researched
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Our Top Picks
Monistat
Best of the Best
Monistat
One-Day Yeast Infection Treatment
Bottom Line
The most powerful yeast infection dosage you can buy over the counter by one of the most trusted brands on the market. Results are fast and effective for most users.
Shop Now
Amazon Basic Care
Best Bang for the Buck
Amazon Basic Care
Miconazole 1 One-Day Treatment
Bottom Line
An effective, one-dose treatment by a lesser known brand that will save you a few dollars. Worth the possible side effects for customers who want fast, affordable relief.
Shop Now
Vagistil
Top Pick
Vagistil
Single Dose Yeast Infection Treatment, 3 Pack
Bottom Line
While this one-dose treatment isn't as likely as some competitors to cause side effects, it may not work as well either.
Shop Now
Monistat
Top Pick
Monistat
Three-Day Yeast Infection Treatment
Bottom Line
Choose this three-day treatment if you prefer a milder dose each time or tend to experience side effects after using one-day treatment options.
Shop Now
Monistat
Top Pick
Monistat
Seven-Day Yeast Infection Treatment
Bottom Line
Although not as convenient as one- or three-day treatments, this classic seven-day option is worth considering for users who like to distribute the medication over several days.
Shop Now
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